Dr Victoria Cogger
Lecturer
Medicine, Concord Clinical School ANZAC Research Institute
C22 - Concord Hospital
The University of Sydney
NSW 2006 Australia
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Current national competitive grants
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2007
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Caloric restriction ageing and the liver sinusoidal endothelium: mechanisms and implications
Le Couteur D, Hilmer S, Cogger V, Frazer R, De Cabo R.
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| NHMRC Project Grant |
$353,000 over 3 years |
Select publications 2008 Cogger, V, Arias, I, Warren, A, McMahon, A, Kiss, D, Avery, V, Le Couteur, D. The response of fenestrations, actin and caveolin-1 to vascular endothelial growth factor in SK Hep1 cells (a liver endothelial cell line). American journal of physiology. Gastrointestinal and liver physiology. 2008; 295 [ Abstract] 2007 Cheluvappa, R, Hilmer, S, Kwun, S, Cogger, V, Le Couteur, D. Effects of old age on hepatocyte oxygenation. Annals of the New York Academy of Sciences. 2007; 1114: 88-92 [ Abstract] Le Couteur, D, Cogger, V, McCuskey, R, de Cabo, R, Smedsrod, B, Sorensen, K, Warren, A, Fraser, R. Age-related changes in the liver sinusoidal endothelium are a mechanism for dyslipidemia. Annals of the New York Academy of Sciences. 2007; 1114: 79-87 [ Abstract] Cheluvappa, R, Hilmer, S, Kwun, S, Jamieson, H, O'reilly, J, Muller, M, Cogger, V, Le Couteur, D. The effect of old age on liver oxygenation and the hepatic expression of VEGF and VEGFR2. Experimental gerontology. 2007; 42: 1012-1019 [ Abstract] Hilmer, S, Cogger, V, Le Couteur, D. Basal activity of Kupffer cells increases with old age. The journals of gerontology. Series A, Biological sciences and medical sciences. 2007; 62: 973-978 [ Abstract] Jamieson, H, Cogger, V, Twigg, S, McLennan, S, Warren, A, Cheluvappa, R, Hilmer, S, Fraser, R, de Cabo, R, Le Couteur, D. Alterations in liver sinusoidal endothelium in a baboon model of type 1 diabetes. Diabetologia. 2007; 50: 1969-1976 [ Abstract] Jamieson, H, Hilmer, S, Cogger, V, Warren, A, Cheluvappa, R, Abernethy, D, Everitt, A, Fraser, R, de Cabo, R, Le Couteur, D. Caloric restriction reduces age-related pseudocapillarization of the hepatic sinusoid. Experimental gerontology. 2007; 42: 374-378 [ Abstract] 2006 Cogger, V, Hilmer, S, Sullivan, D, Muller, M, Fraser, R, Le Couteur, D. Hyperlipidemia and surfactants: The liver sieve is a link. Atherosclerosis. 2006; 189: 273-81 [ Abstract] Le Couteur, D, Cogger, V, Hilmer, S. Aging, atherosclerosis and the liver sieve. In: New research on atherosclerosis. New York: Nova Biomedical 2006. p. 19-44. 2005 Hilmer, S, Cogger, V, Fraser, R, McLean, A, Sullivan, D, Le Couteur, D. Age-related changes in the hepatic sinusoidal endothelium impede lipoprotein transfer in the rat. Hepatology (Baltimore, Md.). 2005; 42: 1349-54 [ Abstract] Warren, A, Bertolino, P, Cogger, V, McLean, A, Fraser, R, Couteur, D. Hepatic pseudocapillarization in aged mice. Experimental gerontology. 2005; 40: 807-12 [ Abstract] 2004 Cogger, V, Muller, M, Fraser, R, McLean, A, Khan, J, Le Couteur, D. The effects of oxidative stress on the liver sieve. Journal of hepatology. 2004; 41: 370-6 [ Abstract] Hilmer, S, Cogger, V, Muller, M, Le Couteur, D. The hepatic pharmacokinetics of doxorubicin and liposomal doxorubicin. Drug metabolism and disposition: the biological fate of chemicals. 2004; 32: 794-9 [ Abstract] Cogger, V, Warren, A, Fraser, R, Ngu, M, McLean, A, Le Couteur, D. Preliminary analysis of the sinusoidal endothelium and space of Disse in ageing Papio hamadrayas. Comparative hepatology [electronic resource]. 2004; 3 Suppl 1 [ Abstract] Hilmer, S, Warren, A, Cogger, V, Fraser, R, McLean, A, Sullivan, D, Le Couteur, D. The effect of aging on the immunohistochemistry of apolipoprotein E in the liver. Experimental gerontology. 2004; 39: 53-7 [ Abstract] 2003 McLean, A, Cogger, V, Chong, G, Warren, A, Markus, A, Dahlstrom, J, Le Couteur, D. Age-related pseudocapillarization of the human liver. Journal Of Pathology. 2003; 200: 112-117 Cogger, V, Warren, A, Fraser, R, Ngu, M, Mclean, A, Le Couteur, D. Hepatic sinusoidal pseudocappilarization with aging in the non-human primate. Experimental Gerontology. 2003; 38: 1101-1107 2002 Le Couteur, D, Fraser, R, Cogger, V, McLean, A. Hepatic pseudocapillarisation and atherosclerosis in ageing. Lancet. 2002; 359: 1612-1615 2001 Cogger, V, Markus, M, Harvey, P, Ansselin, A, McLean, A, Le Couteur, D, Yin, Z. Pseudocapillarization and associated energy limitation in the aged rat liver. In: Hepatology. Philadelphia, London, New York, St. Louis, Sydney, Toronto: Wb Saunders Company 2001. p. 171-199. Cogger, V, Ansselin, A, Le Couteur, D, McLean, A, Mross, P, Hosie, M. The effect of acute oxidative stress on the ultrastructure of the perfused rat liver. Pharmacology & Toxicology. 2001; 174: 338-341 [ Hide publications]
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