Professor Jill Trewhella
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School of Molecular and Microbial Biosciences
G08 - Biochemistry Building |
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Themes | Research interests | Grants | Keywords | International links
Themes
Infection and Immunological Conditions; Neurosciences and Mental Health
Research interests
Jill Trewhella is a biophysicist who uses physical methods to study bio-molecular structures as a basis for understanding their function. A major focus of her work is on the structural biology of how bio-molecules interact and communicate in order to carry out functions that involve multiple molecular actors working in concert. This work requires a multidisciplinary approach using molecular biology, biochemistry, and biophysical tools. One frequently used biophysical tool is the small-angle scattering of x-rays and neutrons in order to probe the solution conformations of proteins and the complexes they form in a wide variety of conditions and states of activity.
Current national competitive grants*
2009
Molecular Mechanisms of two-component signal transduction in bacteria
Trewhella J, Guss M
ARC Discovery Project ($420,000 over 3 years)
2008
Transcriptional complexes in haematopiesis and T-cell Leukaemia
Matthews J, Guss M, Trewhella J
NHMRC Project Grant ($535,500 over 3 years)
Inhibition of histidine kinase signal sensing: a novel paradigm for antimicrobial development
King G, Guss M, Trewhella J
NHMRC Research Project Shared Support ($180,000 over 3 years)
2007
Studies of the dynamic language of bio-molecular communication and signalling
Trewhella J
ARC Discovery Project ($390,000 over 3 years)
Structural Biology Centre for HIV/Host Interactions in Trafficking and Assembly
Trewhella J
National Institutes of Health (USA) Research Support ($142,742 over 5 years)
* Grants administered through the University of Sydney
International links
United States. (National Institutes of Standards Technology) Collaborator.
United States. (University of Utah) Co-investigators.
France. (Institut Laue Langevin) Collaboration.
United States. (University of Utah) Collaborators.